Yeah, you can use just about any software with that GPS.

If you are looking for Street navigation I like the Delorme Street Atlas.

If you are looking for Topo maps, they are expensive but the National Geographic TOPO! State Series is the way to go.

There is a program called GPSgate that allows you to run more than one GPS enabled program at the same time. It's a great little utility if you ever run across the need. http://franson.com/gpsgate/