I run them on DR's, but haven't had them long enough to comment on the mileage (maybe 5K so far?). I also have a 3 inch susp. lift, so can't help you there either. But, the tires are fanatastic and ride great. No problem with balance or anything... they ride smooth as buttah! I've aired them down to about 16 lbs on the trail with no problem. Don't see much point in going any lower than that. I run 32 - 34 lbs on the street with them.