Flycacher- why would headers be incompatible with the stock cats?

One of the biggest advantages of headers for VG33 engine owners is that they permanently solve the cracked exhaust manifold/stud breaking problem. Even if they didn't also offer some kind of performance advantage, with or without high-flow cats, that might be worth it to some.
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4x4 in uppercase is $X$!!!
1997 R50: VG33E/RE4R01A/TX10/3.7/R200A/ARB/4.636/H233B/ARB/4.636/321150R15