I just noticed its not only a 4 banger, but its a 2x4...so its performance would be wooden no matter what he does.
Yeah - the "worth it" part is what triggered the "no" responses.
If he asked if it were possible, sure, its possible...hell, he could have asked if its possible to take a Fiat 124 and install a turbine off an Abrams Tank, sure its possible....maybe impractical, but, possible.
The BEST bet is to trade the truck for one with what he wants...bang - DONE.
The next mess would be to remove the 4 banger drive train, and install a 6 banger drivetrain...SC if desired, etc.
Lets face it, a super charged 4 will not be much better if at all, than the natural 6 anyway.

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- TJ
2001 Xterra '03 VG33, SE 5 spd, 305/70/16's, Revolvers, UBSkidderz, Doubled AAL's, 3"SL/2"BL, winch/bumpers, skids, sliders, OBA, Snorkel, pine stripes....
Friends don't let friends drive stock.
http://www.gifsoup.com/view/501230/tj-tackling-crawlers-ridge-o.gif