Speaking of Topo stuff, I highly recommend Wildflower Topo States Series (recently purchased by National Geographic).
Expensive, but it easily puts DeLorme's novice attempt to shame in quality, ease of use and speed.
http://www.topo.com/products/state.html

I also tried Maptech Terrain Navigator, but after finding a dozen fatal bugs and design flaws, I returned it (can't name routes at creation, have to rename them after, can't give meaningful names to waypoints during creation of a route, have to do each one after, route name uploaded to GPS unit changes and has to be renamed on the GPS). The interface was also cumbersome, based on their old 16 bit version.

Downloading scans is fun, and useful if you're traveling out of state, but if you wheel in one state, drop the cash on Topo State Series.