I'm wanting that size for my Fronty this summer. Dunlop, Bridgestone, Interco, and a few others have tires in that size. That TRXUS tire is available in that size, and that's what I'm thinking I'll get.
You're right about clearance, width is usually the issue, even after a lift. I think a little inner-fender magic will cure any issues that would come up with that size.