I haven't really been following the season, but here's my up-in-the-air picks.

Upsets:

Midwest:
Tulsa over Dayton.
Alabama over Indiana (not really an upset, imo)
Midwest final: Kentucky vs. Marquette. Kentucky wins.

West:
Wisconsin-Milwaukee over Notre Dame.
Central Michigan over Creighton.
West Final: Arizona over Duke.

South:
UNC Wilmington over Maryland.
South Final: Florida over Texas.

East:
Butler over Mississippi State.
Louisville over Oklahoma.
Saint Joe's over Wake Forest.
East Final: Syracuse over Louisville.

Final Four:
Florida over Syracuse.
Arizona over Kentucky.

Florida over Arizona for the title.
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"Nature has constituted utility to man the standard and test of virtue. Men living in different countries, under different circumstances, different habits and regimens, may have different utilities; the same act, therefore, may be useful and consequently virtuous in one country which is injurious and vicious in another differently circumstanced" - Thomas Jefferson, moral relativist