Pathy VQs take premium fuel, but have more power and get slightly better mileage. R50 Pathfinders ride pretty smooth with coils all around so if you do a lot of street driving consider that.

If you have intentions of putting much larger tires than stock on whatever you get, the X might be the better bet, as it takes a bit more custom modification and ingenuity to get larger than 32s on an R50.